BDBM707064 7-(2-Methyl-2-(4- (trifluoromethyl)phenoxy)propyl)- 2-thia-7-azaspiro[3.5]nonane 2,2-dioxide::US20240400579, Example 138

SMILES CC(C)(CN1CCC2(CC1)CS(=O)(=O)C2)Oc1ccc(C(F)(F)F)cc1

InChI Key InChIKey=ALJFTBRBCSXKBW-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 707064   

LigandPNGBDBM707064(7-(2-Methyl-2-(4- (trifluoromethyl)phenoxy)propyl)...)
Affinity DataKi:  5.04nMAssay Description:Compounds were prepared in a 96-well U bottom plate using an Echo550 machine and 10 mM compound DMSO stock solution, followed by an 8-dose 5-fold ser...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
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TargetEmopamil-binding protein-like(Human)
Genentech

US Patent
LigandPNGBDBM707064(7-(2-Methyl-2-(4- (trifluoromethyl)phenoxy)propyl)...)
Affinity DataKi:  16nMAssay Description:Determination of equilibrium dissociation constant Kd of radioligand: Membrane prepared as described above was pre-incubated with PVT-WGA SPA beads (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
Go to US Patent