BDBM707051 6-(2,2-Dimethyl-3-(4- (trifluoromethyl)phenyl)propyl)- 2-thia-6-azaspiro[3.4]octane-2,2- dioxide::US20240400579, Example 125

SMILES CC(C)(Cc1ccc(C(F)(F)F)cc1)CN1CCC2(C1)CS(=O)(=O)C2

InChI Key InChIKey=XRVKQYQMCBHMEF-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 707051   

LigandPNGBDBM707051(6-(2,2-Dimethyl-3-(4- (trifluoromethyl)phenyl)prop...)
Affinity DataKi:  4.02nMAssay Description:Compounds were prepared in a 96-well U bottom plate using an Echo550 machine and 10 mM compound DMSO stock solution, followed by an 8-dose 5-fold ser...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
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TargetEmopamil-binding protein-like(Human)
Genentech

US Patent
LigandPNGBDBM707051(6-(2,2-Dimethyl-3-(4- (trifluoromethyl)phenyl)prop...)
Affinity DataKi:  56nMAssay Description:Determination of equilibrium dissociation constant Kd of radioligand: Membrane prepared as described above was pre-incubated with PVT-WGA SPA beads (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
Go to US Patent