BDBM707021 6-(2-Methyl-3-(4-(tert- pentyl)phenyl)propyl)-2-thia-6- azaspiro[3.4]octane 2,2-dioxide::US20240400579, Example 107

SMILES CCC(C)(C)c1ccc(CC(C)CN2CCC3(C2)CS(=O)(=O)C3)cc1

InChI Key InChIKey=FNALRUNZUQEFHH-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 707021   

LigandPNGBDBM707021(6-(2-Methyl-3-(4-(tert- pentyl)phenyl)propyl)-2-th...)
Affinity DataKi:  10.3nMAssay Description:Compounds were prepared in a 96-well U bottom plate using an Echo550 machine and 10 mM compound DMSO stock solution, followed by an 8-dose 5-fold ser...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
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TargetEmopamil-binding protein-like(Human)
Genentech

US Patent
LigandPNGBDBM707021(6-(2-Methyl-3-(4-(tert- pentyl)phenyl)propyl)-2-th...)
Affinity DataKi:  23nMAssay Description:Determination of equilibrium dissociation constant Kd of radioligand: Membrane prepared as described above was pre-incubated with PVT-WGA SPA beads (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
Go to US Patent