BDBM706994 US20240400537, Example EX-C-27

SMILES Cc1c(OCC(F)F)nnc(N2C[C@]3(CC[C@](c4cccc(F)c4)(N(C)C)CC3)NC2=O)c1C

InChI Key InChIKey=MGALDGVIPUDDKE-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 706994   

TargetMu-type opioid receptor(Human)
Gruenenthal

US Patent
LigandPNGBDBM706994(US20240400537, Example EX-C-27)
Affinity DataKi:  0.700nMAssay Description:The human μ-opioid (hMOP) receptor binding assay was performed as an filtration-based radio agonist binding assay. Cell membranes of transfected CHO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
Go to US Patent

TargetNociceptin receptor(Human)
Gruenenthal

US Patent
LigandPNGBDBM706994(US20240400537, Example EX-C-27)
Affinity DataKi:  1nMAssay Description:The human nociceptin (hNOP) receptor binding assay was performed as an filtration-based radio agonist binding assay. Cell membrane homogenates of tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
Go to US Patent