BDBM706974 US20240400537, Example EX-C-07

SMILES Cc1cc(OC(F)(F)F)cnc1N1C[C@]2(CC[C@](c3cccc(F)c3)(N(C)C)CC2)NC1=O

InChI Key InChIKey=NCJGYBAEPVRXNF-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 706974   

TargetMu-type opioid receptor(Human)
Gruenenthal

US Patent
LigandPNGBDBM706974(US20240400537, Example EX-C-07)
Affinity DataKi:  3.5nMAssay Description:The human μ-opioid (hMOP) receptor binding assay was performed as an filtration-based radio agonist binding assay. Cell membranes of transfected CHO ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
Go to US Patent

TargetNociceptin receptor(Human)
Gruenenthal

US Patent
LigandPNGBDBM706974(US20240400537, Example EX-C-07)
Affinity DataKi:  3.80nMAssay Description:The human nociceptin (hNOP) receptor binding assay was performed as an filtration-based radio agonist binding assay. Cell membrane homogenates of tra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
Go to US Patent