BDBM7069 (4R,5S,6S,7R)-1,3-bis(cyclopropylmethyl)-5,6-dihydroxy-4,7-bis(naphthalen-2-ylmethyl)-1,3-diazepan-2-one::(4R,5S,6S,7R)-Hexahydro-5,6-dihydroxy-1,3-bis-(cyclopropylmethyl)-4,7-bis( -naphthylmethyl)-2H-1,3-diazapin-2-one::Substituted Cyclic Urea 59

SMILES O[C@@H]1[C@@H](O)[C@@H](Cc2ccc3ccccc3c2)N(CC2CC2)C(=O)N(CC2CC2)[C@@H]1Cc1ccc2ccccc2c1

InChI Key InChIKey=DQHWWSRQFWBYKQ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 7069   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandPNGBDBM7069((4R,5S,6S,7R)-Hexahydro-5,6-dihydroxy-1,3-bis-(cyc...)
Affinity DataKi:  4.30nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2006
Entry Details Article
PubMed