BDBM706750 US20240398737, Compound I-1-CoA

SMILES CC(C)(CCCCc1ccc(CCCCC(C)(C)C(=O)CCNC(=O)CCNC(=O)C(O)C(C)(C)COP(=O)([O-])OP(=O)([O-])OCC2OC(n3cnc4c(N)ncnc43)C(O)C2OP(=O)([O-])[O-])cc1)C(=O)O

InChI Key InChIKey=YGLCBTNUUJPEOY-UHFFFAOYSA-J

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 706750   

TargetAcetyl-CoA carboxylase 1(Human)
Espervita Therapeutics

US Patent
LigandPNGBDBM706750(US20240398737, Compound I-1-CoA)
Affinity DataIC50: 1.63E+4nMAssay Description:Table 3: Human ACC1 (Cat #50202 Lot #120830) and ACC2 (Cat #50201 Lot #160217) were obtained from BPS Biosciences, San Diego, CA 92121. Human ACC1 ha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
Go to US Patent

TargetAcetyl-CoA carboxylase 2(Human)
Espervita Therapeutics

US Patent
LigandPNGBDBM706750(US20240398737, Compound I-1-CoA)
Affinity DataIC50: 9.41E+3nMAssay Description:Table 3: Human ACC1 (Cat #50202 Lot #120830) and ACC2 (Cat #50201 Lot #160217) were obtained from BPS Biosciences, San Diego, CA 92121. Human ACC1 ha...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
Go to US Patent

TargetATP-citrate synthase(Human)
Espervita Therapeutics

US Patent
LigandPNGBDBM706750(US20240398737, Compound I-1-CoA)
Affinity DataIC50: 3.34E+3nMAssay Description:Table 4: ATP citrate lyase was obtained from Sino Biological Inc. Cat #11769-H07B, Lot #LC08DE1701. It was prepared from a DNA sequence encoding the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
Go to US Patent