BDBM706743 US12157739, Example 11

SMILES COc1ccc(Cn2cnc3nc(-n4cc(C(=O)O)cn4)[nH]c(=O)c32)cc1

InChI Key InChIKey=MHURXTSQLQHZAN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 706743   

TargetEgl nine homolog 1 [184-418](Human)
Kissei Pharmaceutical

US Patent
LigandPNGBDBM706743(US12157739, Example 11)
Affinity DataIC50: 440nMAssay Description:An enzyme (human PHD2 184-418) and the substrate were diluted with an assay buffer (pH 7.4) containing 10 mM HEPES, 150 mM NaCl, 10 μM MnCl2-4H2O, 2 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/14/2025
Entry Details
Go to US Patent