BDBM706718 US20240383924, Compound 029

SMILES Oc1cc(-c2c(Cl)cc3c(N4C5CCC4CNC5)nc(OC[C@@]45CCCN4C[C@H](F)C5)nc3c2F)c2ccccc2c1

InChI Key InChIKey=WQOVFTZNEMFBJO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 706718   

TargetGTPase KRas [G12D](Human)
Usynova Pharmaceuticals

US Patent
LigandPNGBDBM706718(US20240383924, Compound 029)
Affinity DataIC50: 38.6nMAssay Description:1) KRAS nucleotide exchange buffer20 mL of 1000 mM HEPES, 20 mL of 500 mM EDTA, 10 mL of 5 M sodium chloride, 0.1 mL of 100% Tween 20, and 949.9 mL o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent