BDBM706717 US20240383924, Compound 022

SMILES Nc1nc2c(-c3c(F)cc4c(N5CC6CCC(C5)N6)nc(OC[C@@]56CCCN5C[C@H](F)C6)nc4c3F)ccc(F)c2s1

InChI Key InChIKey=NDMZOLXCGUZOFQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 706717   

TargetGTPase KRas [G12D](Human)
Usynova Pharmaceuticals

US Patent
LigandPNGBDBM706717(US20240383924, Compound 022)
Affinity DataIC50: 6.60nMAssay Description:1) KRAS nucleotide exchange buffer20 mL of 1000 mM HEPES, 20 mL of 500 mM EDTA, 10 mL of 5 M sodium chloride, 0.1 mL of 100% Tween 20, and 949.9 mL o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/12/2025
Entry Details
Go to US Patent