BDBM706123 JHU1220501::US20240382629, Example 8

SMILES N#C[C@@H]1CCCN1C(=O)CNC(=O)c1ccnc2cc(F)ccc12

InChI Key InChIKey=HXQISXPMFJMCQZ-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 706123   

TargetDipeptidyl peptidase 4(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM706123(JHU1220501 | US20240382629, Example 8)
Affinity DataIC50: 2.00E+7nMAssay Description:PSMA binding affinities of the compounds were determined using a competitive inhibition assay as previously reported. Banerjee et al., 2011. FAP, pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetPresequence protease, mitochondrial(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM706123(JHU1220501 | US20240382629, Example 8)
Affinity DataIC50: 522nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM706123(JHU1220501 | US20240382629, Example 8)
Affinity DataIC50: 2.16nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Human)
The Johns Hopkins University

US Patent
LigandPNGBDBM706123(JHU1220501 | US20240382629, Example 8)
Affinity DataKi:  0.433nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/11/2025
Entry Details
Go to US Patent