BDBM705296 US20240376114, Compound 71

SMILES O=C(/C=C 1cnc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)n1)NNc1ccccn1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 705296   

TargetProtein Rev(Human immunodeficiency virus type 1)
Karyopharm Therapeutics

US Patent
LigandPNGBDBM705296(US20240376114, Compound 71)
Affinity DataIC50: 1.00E+3nMAssay Description:The ability of exemplary compounds of the invention to inhibit CRM1-mediated nuclear export was assessed in a RevGFP assay. Rev is a protein from hum...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
Go to US Patent