BDBM704992 2-((1H-pyrrolo[2,3-b]pyridin-5-yl) oxy)-4-(2-((R or S)-2-(2- isopropylphenyl)-4-(4- methoxybenzyl)piperazin-1-yl)-7- azaspiro[3.5]nonan-7-yl)-N-((3- nitro-4-((((R)-4-(oxetan-3-yl) morpholin-2-yl)methyl)amino) phenyl)sulfonyl)benzamide::US20240376097, Example 84
SMILES COc1ccc(CN2CCN(C3CC4(CCN(c5ccc(C(=O)NS(=O)(=O)c6ccc(NC[C@@H]7CN(C8COC8)CCO7)c([N+](=O)[O-])c6)c(Oc6cnc7[nH]ccc7c6)c5)CC4)C3)[C@H](c3ccccc3C(C)C)C2)cc1
InChI Key InChIKey=PWKPZQKHIPEVPJ-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 704992
Affinity DataIC50: 0.0280nMAssay Description:Compounds disclosed herein were tested for blocking of Bcl-2 protein with its ligand in an assay based on Time-Resolved Fluorescence Resonance Energy...More data for this Ligand-Target Pair
Affinity DataIC50: 0.150nMAssay Description:Compounds disclosed herein were tested for blocking of Bcl-2-G101V protein with its ligand in an assay based on time-resolved fluorescence resonance ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0490nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0280nMAssay Description:Compounds disclosed herein were tested for blocking of Bcl-2 protein with its ligand in an assay based on Time-Resolved Fluorescence Resonance Energy...More data for this Ligand-Target Pair