BDBM704924 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-N- ((4-((((1r,4r)-4-bydroxy-4- methylcyclohexyl)methyl)amino)-3- nitrophenyl)sulfonyl)-4-(2-((R or S)-2-(2- isopropylphenyl)-4-(2- methoxyethyl)piperazin-1-yl)-7- azaspiro[3.5]nonan-7-yl)benzamide::US20240376097, Example 13b
SMILES COCCN1CCN(C2CC3(CCN(c4ccc(C(=O)NS(=O)(=O)c5ccc(NC[C@H]6CC[C@@](C)(O)CC6)c([N+](=O)[O-])c5)c(Oc5cnc6[nH]ccc6c5)c4)CC3)C2)[C@H](c2ccccc2C(C)C)C1
InChI Key InChIKey=KDVNOMQZAHHERU-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 704924
Affinity DataIC50: 0.00700nMAssay Description:Compounds disclosed herein were tested for blocking of Bcl-2 protein with its ligand in an assay based on Time-Resolved Fluorescence Resonance Energy...More data for this Ligand-Target Pair
Affinity DataIC50: 0.150nMAssay Description:Compounds disclosed herein were tested for blocking of Bcl-2-G101V protein with its ligand in an assay based on time-resolved fluorescence resonance ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0900nMAssay Description:Selected compounds disclosed herein were tested for blocking of Bcl-2D 103Y protein with its ligand in an assay based on time-resolved fluorescence r...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0680nMAssay Description:Compounds disclosed herein were tested for blocking of Bcl-2 protein with its ligand in an assay based on Time-Resolved Fluorescence Resonance Energy...More data for this Ligand-Target Pair