BDBM704458 US20240374595, Example 37

SMILES Cc2c(NC(=O)c1ccc(CNCCO)cn1)cccc2c5cccc(NC(=O)c4ccc(CN3CC[C@@H](O)C3)cn4)c5C

InChI Key InChIKey=RZSFQSQQAPWQPB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 704458   

TargetProgrammed cell death 1 ligand 1(Human)
Arbutus Biopharma

US Patent
LigandPNGBDBM704458(US20240374595, Example 37)
Affinity DataIC50: 0.800nMAssay Description:PD-L1 His protein was prepared and added at the final concentration of 6 nM in the White opaque 384 well plate (Corning cat #3824BC). PD-L1 small mol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/20/2025
Entry Details
Go to US Patent