BDBM704306 US20240374581, Compound 1
SMILES [2H]C1([2H])OC2=CC3C[C@@H](C)N(CC(F)(F)CO)[C@H](c4ccc(NC5CN(CCCF)C5)cn4)C3C=C2O1
InChI Key InChIKey=FULNJTDKGPTVII-DOBBINOXSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 704306
Affinity DataIC50: 1.31E+4nMAssay Description:Table 7: A 100 mM PBS buffer was prepared. A 0.25 mg/mL microsome solution, a 7.5 mM MgCl2 and a 5 mM NADPH solution were prepared using the buffer. ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.96E+4nMAssay Description:Table 7: A 100 mM PBS buffer was prepared. A 0.25 mg/mL microsome solution, a 7.5 mM MgCl2 and a 5 mM NADPH solution were prepared using the buffer. ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Table 6: I. Experimental Materials and Instruments1. Phosphate buffer (20×PBS, purchased from Sangon);2. NADPH (ACROS, A2646-71-1);3. Human liver mic...More data for this Ligand-Target Pair