BDBM704096 N-(3-(difluoromethyl)-1-(1-(4-(4-(3-(2,6-dioxopiperidin-3-yl)-4-fluorobenzoyl)piperazin-1-yl)butanoyl)piperidin-4-yl)-1H-pyrazol-4-yl)-5-morpholinopyrazolo[1,5-a]pyrimidine-3-carboxamide::US20240368194, Example 62

SMILES O=C1CCC(c2cc(C(=O)N3CCN(CCCC(=O)N4CCC(n5cc(NC(=O)c6cnn7ccc(N8CCOCC8)nc67)c(C(F)F)n5)CC4)CC3)ccc2F)C(=O)N1

InChI Key InChIKey=YMSSLTSRSSNEAU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 704096   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Shanghai Leadingtac Pharmaceutical

US Patent
LigandPNGBDBM704096(N-(3-(difluoromethyl)-1-(1-(4-(4-(3-(2,6-dioxopipe...)
Affinity DataIC50: 28.9nMAssay Description:The KinEASE-STK SI serine/threonine kinase kit (Cisbio) was used to test the inhibitory effect of the compounds on the IRAK4 kinase activity, and the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
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