BDBM704035 2-((6-(5-Amino-4-methylpyridin-3-yl)cinnolin- 3-yl)amino)-6-isopropyl-5,6-dihydro-4H- pyrazolo[1,5-d][1,4]diazepin-7(8H)-one::US20240368170, Compound 28

SMILES Cc1c(N)cncc1-c1ccc2nnc(Nc3cc4n(n3)CC(=O)N(C(C)C)CC4)cc2c1

InChI Key InChIKey=YLFDXLDPOUUHFC-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 704035   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Genentech

US Patent

LigandBDBM704035(2-((6-(5-Amino-4-methylpyridin-3-yl)cinnolin- 3-yl...)Copy SMILESCopy InChI

Affinity DataKi:  40nMAssay Description:HPK-FL enzyme phosphorylates Biotin-SLP-76 substrate in the presence of ATP at 1 mM and varying concentrations of test compound. Product is detected ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/14/2025
Entry Details
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