BDBM704028 US20240368170, Compound 22::cis-N-(8-Amino-6-(4-cyclopropylpyridin-3- yl)cinnolin-3-yl)-2- fluorocyclopropanecarboxamide

SMILES Nc1cc(-c2cnccc2C2CC2)cc2cc(NC(=O)C3CC3F)nnc12

InChI Key InChIKey=WQRRLGORFLZSSQ-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 704028   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Genentech

US Patent

LigandBDBM704028(cis-N-(8-Amino-6-(4-cyclopropylpyridin-3- yl)cinno...)Copy SMILESCopy InChI

Affinity DataKi:  31nMAssay Description:For the binding assay, 4 μL 2×HPK1 and Eu-anti-GST antibody were added to each well of the assay plate using a Multidrop reagent dispenser. The solut...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/14/2025
Entry Details
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