BDBM704026 US20240368170, Compound 20::trans-8-Amino-6-(4-ethylpyridin-3-yl)cinnolin- 3-yl)-2-cyanocyclopropanecarboxamide

SMILES CCc1ccncc1-c1cc(N)c2nnc(NC(=O)C3CC3C#N)cc2c1

InChI Key InChIKey=NUHVUYYZKDCBAG-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 704026   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Genentech

US Patent

LigandBDBM704026(trans-8-Amino-6-(4-ethylpyridin-3-yl)cinnolin- 3-y...)Copy SMILESCopy InChI

Affinity DataKi:  13nMAssay Description:For the binding assay, 4 μL 2×HPK1 and Eu-anti-GST antibody were added to each well of the assay plate using a Multidrop reagent dispenser. The solut...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/14/2025
Entry Details
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