BDBM704020 1-[8-Amino-6-(4-ethyl-3-pyridyl)cinnolin-3-yl]- 3-(2,2,2-trifluoroethyl)urea::US20240368170, Compound 14

SMILES CCc1ccncc1-c1cc(N)c2nnc(NC(=O)NCC(F)(F)F)cc2c1

InChI Key InChIKey=KTHBVYQGWLQHFX-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 704020   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Genentech

US Patent

LigandBDBM704020(1-[8-Amino-6-(4-ethyl-3-pyridyl)cinnolin-3-yl]- 3-...)Copy SMILESCopy InChI

Affinity DataKi:  22nMAssay Description:For the binding assay, 4 μL 2×HPK1 and Eu-anti-GST antibody were added to each well of the assay plate using a Multidrop reagent dispenser. The solut...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/14/2025
Entry Details
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