BDBM704014 1-[8-Amino-6-(1-methylpyrazol-4-yl)cinnolin- 3-yl]-3-isopropyl-urea::US20240368170, Compound 8

SMILES CC(C)NC(=O)Nc1cc2cc(-c3cnn(C)c3)cc(N)c2nn1

InChI Key InChIKey=RUAAHBBCWLLRCM-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 704014   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Genentech

US Patent

LigandBDBM704014(1-[8-Amino-6-(1-methylpyrazol-4-yl)cinnolin- 3-yl]...)Copy SMILESCopy InChI

Affinity DataKi:  21nMAssay Description:For the binding assay, 4 μL 2×HPK1 and Eu-anti-GST antibody were added to each well of the assay plate using a Multidrop reagent dispenser. The solut...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/14/2025
Entry Details
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