BDBM703819 (3R)-3-amino-8-fluoro-7-[5-(1- fluoro-1-methyl-ethyl)-1,2,4- oxadiazol-3-yl]-5-[(4- fluorophenyl)methyl]-1,1- dioxo-2,3-dihydro-1lambda6,5- benzothiazepin-4-one (*)::US20240368150, Example 358

SMILES CC(C)(F)c1nc(-c2cc3c(cc2F)S(=O)(=O)C[C@H](N)C(=O)N3Cc2ccc(F)cc2)no1

InChI Key InChIKey=RCHBXSFRJMWHJL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 703819   

TargetDiacylglycerol kinase alpha(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM703819((3R)-3-amino-8-fluoro-7-[5-(1- fluoro-1-methyl-eth...)
Affinity DataIC50: 2.70E+3nMAssay Description:DGK α and ζ kinase use ATP to phosphorylate the substrate 1,2-dilauroyl-sn-glycerol (DLG, incorporated in the liposomes). ATP is converted to ADP as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetDiacylglycerol kinase zeta(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM703819((3R)-3-amino-8-fluoro-7-[5-(1- fluoro-1-methyl-eth...)
Affinity DataIC50: 122nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent