BDBM703814 (3R)-3-amino-7-[5-(1-amino-2,2,2-trifluoro-1-methyl-ethyl)-1,2,4-oxadiazol-3-yl]-8-fluoro-1,1-dioxo-5-[[4-(trifluoromethoxy)phenyl]methyl]-2,3-dihydro-1λ6,5-benzothiazepin-4-one::US20240368150, Example 331

SMILES CC(N)(c1nc(-c2cc3c(cc2F)S(=O)(=O)C[C@H](N)C(=O)N3Cc2ccc(OC(F)(F)F)cc2)no1)C(F)(F)F

InChI Key InChIKey=VPOBYDIVNCVOCA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 703814   

TargetDiacylglycerol kinase alpha(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM703814((3R)-3-amino-7-[5-(1-amino-2,2,2-trifluoro-1-methy...)
Affinity DataIC50: 857nMAssay Description:DGK α and ζ kinase use ATP to phosphorylate the substrate 1,2-dilauroyl-sn-glycerol (DLG, incorporated in the liposomes). ATP is converted to ADP as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetDiacylglycerol kinase zeta(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM703814((3R)-3-amino-7-[5-(1-amino-2,2,2-trifluoro-1-methy...)
Affinity DataIC50: 176nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent