BDBM703811 (3R)-3-amino-5-[(4- chlorophenyl)methyl]-7-[5- (4,6-dimethyl-3-pyridyl)-1,2,4- oxadiazol-3-yl]-8-fluoro-1,1- dioxo-2,3-dihydro-1lambda6,5- benzothiazepin-4-one (*)::US20240368150, Example 313

SMILES Cc1cc(C)c(-c2nc(-c3cc4c(cc3F)S(=O)(=O)C[C@H](N)C(=O)N4Cc3ccc(Cl)cc3)no2)cn1

InChI Key InChIKey=XGCYMCLRGGYAEM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 703811   

TargetDiacylglycerol kinase alpha(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM703811((3R)-3-amino-5-[(4- chlorophenyl)methyl]-7-[5- (4,...)
Affinity DataIC50: 1.66E+3nMAssay Description:DGK α and ζ kinase use ATP to phosphorylate the substrate 1,2-dilauroyl-sn-glycerol (DLG, incorporated in the liposomes). ATP is converted to ADP as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
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TargetDiacylglycerol kinase zeta(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM703811((3R)-3-amino-5-[(4- chlorophenyl)methyl]-7-[5- (4,...)
Affinity DataIC50: 130nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent