BDBM703809 (3R)-3-amino-5-[(4- chlorophenyl)methyl]-8- fluoro-7-[5-(2-methyl-5- methylsulfonyl-phenyl)-1,2,4- oxadiazol-3-yl]-1,1-dioxo-2,3- dihydro-1lambda6,5-benzothiazepin- 4-one (**)::US20240368150, Example 311

SMILES Cc1ccc(S(C)(=O)=O)cc1-c1nc(-c2cc3c(cc2F)S(=O)(=O)C[C@H](N)C(=O)N3Cc2ccc(Cl)cc2)no1

InChI Key InChIKey=YSJYOTKISQEOGV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 703809   

TargetDiacylglycerol kinase alpha(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM703809((3R)-3-amino-5-[(4- chlorophenyl)methyl]-8- fluoro...)
Affinity DataIC50: 4.37E+4nMAssay Description:DGK α and ζ kinase use ATP to phosphorylate the substrate 1,2-dilauroyl-sn-glycerol (DLG, incorporated in the liposomes). ATP is converted to ADP as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetDiacylglycerol kinase zeta(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM703809((3R)-3-amino-5-[(4- chlorophenyl)methyl]-8- fluoro...)
Affinity DataIC50: 69nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent