BDBM703769 N-benzyl-N-[2- ethyl-4-oxo-3-[[1- [2-(2H-tetrazol-5- yl)phenyl]-4-piper- idyl]methyl]quin- azolin-6-yl]thio- phene-2-carbox- amide::US20240368133, Compound A-246

SMILES CCc1nc2ccc(N(Cc3ccccc3)C(=O)c3cccs3)cc2c(=O)n1CC1CCN(c2ccccc2-c2nn[nH]n2)CC1

InChI Key InChIKey=WUAOVPRYOIGVEK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 703769   

LigandPNGBDBM703769(N-benzyl-N-[2- ethyl-4-oxo-3-[[1- [2-(2H-tetrazol-...)
Affinity DataIC50: 102nMAssay Description:All synthesized ligands were evaluated in a radioligand assay by displacing 125I-[Sar1, Ile8]-Angiotensin II (Perkin Elmer, NEX248050UC) from human A...More data for this Ligand-Target Pair
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Date in BDB:
3/14/2025
Entry Details
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TargetType-1 angiotensin II receptor(Human)
Confo Therapeutics

US Patent
LigandPNGBDBM703769(N-benzyl-N-[2- ethyl-4-oxo-3-[[1- [2-(2H-tetrazol-...)
Affinity DataIC50: 2.67E+4nMAssay Description:All synthesized ligands were evaluated in a radioligand assay by displacing 125I-[Sar1, Ile8]-Angiotensin II (Perkin Elmer, NEX248050UC) from human A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent