BDBM703766 N-[2-ethyl-4-oxo- 3-[[1-[2-(2H- tetrazol-5-yl)phen- yl]-4-piperidyl]- methyl]quinazolin- 6-yl]-N-propyl- thiophene-2-carbox- amide::US20240368133, Compound A-243

SMILES CCCN(C(=O)c1cccs1)c1ccc2nc(CC)n(CC3CCN(c4ccccc4-c4nn[nH]n4)CC3)c(=O)c2c1

InChI Key InChIKey=KYKORMOBINELNF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 703766   

LigandPNGBDBM703766(N-[2-ethyl-4-oxo- 3-[[1-[2-(2H- tetrazol-5-yl)phen...)
Affinity DataIC50: 159nMAssay Description:All synthesized ligands were evaluated in a radioligand assay by displacing 125I-[Sar1, Ile8]-Angiotensin II (Perkin Elmer, NEX248050UC) from human A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent

TargetType-1 angiotensin II receptor(Human)
Confo Therapeutics

US Patent
LigandPNGBDBM703766(N-[2-ethyl-4-oxo- 3-[[1-[2-(2H- tetrazol-5-yl)phen...)
Affinity DataIC50: 1.15E+4nMAssay Description:All synthesized ligands were evaluated in a radioligand assay by displacing 125I-[Sar1, Ile8]-Angiotensin II (Perkin Elmer, NEX248050UC) from human A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent