BDBM703677 2-[[4-[3-fluoro-5- isobutyl-2-(2H- tetrazol-5-yl)phen- yl]piperazin-1-yl]- methyl]-3H-quin- azolin-4-one::US20240368133, Compound A-154

SMILES CC(C)Cc1cc(F)c(-c2nn[nH]n2)c(N2CCN(Cc3nc4ccccc4c(=O)[nH]3)CC2)c1

InChI Key InChIKey=KNGTYFUODJQHMH-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 703677   

TargetType-2 angiotensin II receptor/Low affinity immunoglobulin epsilon Fc receptor(Human)
Confo Therapeutics

US Patent

LigandBDBM703677(2-[[4-[3-fluoro-5- isobutyl-2-(2H- tetrazol-5-yl)p...)Copy SMILESCopy InChI

Affinity DataIC50: 160nMAssay Description:All synthesized ligands were evaluated in a radioligand assay by displacing 125I-[Sar1, Ile8]-Angiotensin II (Perkin Elmer, NEX248050UC) from human A...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/14/2025
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL