BDBM703349 US20240368106, Example 19

SMILES Cc1cc(O[C@H](C)C(=O)N2CCCCC2)cc2oc(=O)cc(-c3ccc(F)cc3)c12

InChI Key InChIKey=ZJGWLOUQMWJHSK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 703349   

TargetDNA-directed RNA polymerase, mitochondrial(Human)
Pretzel Therapeutics

US Patent
LigandPNGBDBM703349(US20240368106, Example 19)
Affinity DataIC50: 500nMAssay Description:Proteins used as transcription factors (POLRMT: NP_005026.3, TFAM: NP_003192.1, TFB2M: NP_071761.1) are diluted from their stocks to working concentr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
Go to US Patent