BDBM70245 6-Amino-4-furan-3-yl-3-methyl-1,4-dihydro-pyrano[2,3-c]pyrazole-5-carbonitrile::6-amino-4-(3-furanyl)-3-methyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile::6-amino-4-(3-furyl)-3-methyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile::6-amino-4-(furan-3-yl)-3-methyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile::6-azanyl-4-(furan-3-yl)-3-methyl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile::MLS000075441::SMR000014497::cid_645331

SMILES Cc1[nH]nc2OC(=N)C(C#N)C(c3ccoc3)c12

InChI Key InChIKey=CTXWYNAARUXPGJ-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 70245   

TargetProtein RecA(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM70245(SMR000014497 | 6-amino-4-(3-furanyl)-3-methyl-2,4-...)
Affinity DataEC50:  1.79E+4nMAssay Description:Keywords: GFP, refolding, reducing reagent, GFP fluorescence Assay Overview: M. tuberculosis harbors three inteins, which interrupt the DnaB, RecA, a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2011
Entry Details
PCBioAssay
TargetProtein RecA(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM70245(SMR000014497 | 6-amino-4-(3-furanyl)-3-methyl-2,4-...)
Affinity DataEC50:  2.25E+3nMAssay Description:Keywords: GFP-RecA intein, protein splicing, refolding, reducing reagent, GFP fluorescence Assay Overview: M. tuberculosis harbors three inteins, whi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/30/2011
Entry Details
PCBioAssay
TargetImportin subunit alpha-1(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM70245(SMR000014497 | 6-amino-4-(3-furanyl)-3-methyl-2,4-...)
Affinity DataEC50: >5.00E+5nMAssay Description:Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2011
Entry Details
PCBioAssay