BDBM701941 ACV-2- 016-A/B::US12129248, Compound ACV-29

SMILES CC(C)(C)c1ccc(/C=N/N=C2NC(=O)C(CC(=O)Nc3ccc(N4CCCC4)cc3)S2)cc1

InChI Key InChIKey=QIPGIHROXMEFHR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 701941   

TargetChromobox protein homolog 2(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM701941(ACV-2- 016-A/B | US12129248, Compound ACV-29)
Affinity DataIC50: 3.90E+4nMAssay Description:The protocol for the CBX7 AlphaScreen was as follows: a standard alpha buffer (50 mM HEPES, 150 mM NaCl, 0.1% w/v BSA, 0.01% w/v Tween20) at pH 8.0 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2025
Entry Details
Go to US Patent

TargetChromobox protein homolog 7(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM701941(ACV-2- 016-A/B | US12129248, Compound ACV-29)
Affinity DataIC50: 0.0380nMAssay Description:The protocol for the CBX7 Fluorescence Polarization assay is as follows: A standard FP buffer (20 mM Tris, 250 mM NaCl, 0.01% w/v Tween20) at pH 8.0 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2025
Entry Details
Go to US Patent

TargetChromobox protein homolog 2(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM701941(ACV-2- 016-A/B | US12129248, Compound ACV-29)
Affinity DataIC50: 1.55E+4nMAssay Description:The protocol for the CBX7 AlphaScreen was as follows: a standard alpha buffer (50 mM HEPES, 150 mM NaCl, 0.1% w/v BSA, 0.01% w/v Tween20) at pH 8.0 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2025
Entry Details
Go to US Patent

TargetChromobox protein homolog 7(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM701941(ACV-2- 016-A/B | US12129248, Compound ACV-29)
Affinity DataIC50: 0.0170nMAssay Description:The protocol for the CBX7 Fluorescence Polarization assay is as follows: A standard FP buffer (20 mM Tris, 250 mM NaCl, 0.01% w/v Tween20) at pH 8.0 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2025
Entry Details
Go to US Patent