BDBM701936 ACV-2- 007-A::US12129248, Compound ACV-24

SMILES O=C(CC2SCC(C(=O)N/N=C/c1cccnc1)NC2=O)Nc4ccc(N3CCCC3)cc4

InChI Key InChIKey=IPXHGOCGMJMKCS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 701936   

TargetChromobox protein homolog 2(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM701936(ACV-2- 007-A | US12129248, Compound ACV-24)
Affinity DataIC50: 6.53E+4nMAssay Description:The protocol for the CBX7 AlphaScreen was as follows: a standard alpha buffer (50 mM HEPES, 150 mM NaCl, 0.1% w/v BSA, 0.01% w/v Tween20) at pH 8.0 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2025
Entry Details
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TargetChromobox protein homolog 7(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM701936(ACV-2- 007-A | US12129248, Compound ACV-24)
Affinity DataIC50: 0.0440nMAssay Description:The protocol for the CBX7 Fluorescence Polarization assay is as follows: A standard FP buffer (20 mM Tris, 250 mM NaCl, 0.01% w/v Tween20) at pH 8.0 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2025
Entry Details
Go to US Patent