BDBM701463 US20240352000, Example 9

SMILES COc3cc(N2CCC(N1CCN(C)CC1)CC2)ccc3Nc6ncc(C(F)(F)F)c(Nc5cccc4CCN(S(C)(=O)=O)c45)n6

InChI Key InChIKey=RBVKGGSNQOZWMQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 701463   

TargetEpidermal growth factor receptor [1-18,20-1210,T790M](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM701463(US20240352000, Example 9)
Affinity DataIC50: 1nMAssay Description:An experiment to measure the activity of the compounds of the present invention against EGFR mutant enzymes was performed as follows using the HTRF s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2025
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor [1-18,20-1210,T790M,C797S](Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM701463(US20240352000, Example 9)
Affinity DataIC50: 1nMAssay Description:An experiment to measure the activity of the compounds of the present invention against EGFR mutant enzymes was performed as follows using the HTRF s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2025
Entry Details
Go to US Patent