BDBM701412 3-(6-Oxo-5-(trifluoromethyl)-1,6-dihydropyridin-3-yl)phenyl (S)-3-(hydroxymethyl)-4-(5-(trifluoromethyl)pyrimidin-2-yl)piperazine-1-carboxylate::US20240351997, Example 142

SMILES O=C(Oc1cccc(-c2c[nH]c(=O)c(C(F)(F)F)c2)c1)N1CCN(c2ncc(C(F)(F)F)cn2)[C@H](CO)C1

InChI Key InChIKey=FKGKWSIUGFCZAV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 701412   

TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Shanghai Qilu Pharmaceutical Research And Development Centre

US Patent
LigandPNGBDBM701412(3-(6-Oxo-5-(trifluoromethyl)-1,6-dihydropyridin-3-...)
Affinity DataIC50: 0.740nMAssay Description:1. Preparation of 384-well histone-coated plate: 25 μL of histone solution was added to each well, and the plate was incubated overnight at 4° C...More data for this Ligand-Target Pair
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Date in BDB:
3/2/2025
Entry Details
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