BDBM701395 2-(6-Oxo-5-(trifluoromethyl)-1,6-dihydropyridin-3-yl)ethyl 8-(5-(trifluoromethyl)pyrimidin-2-yl)-3,8-diazabicyclo[3.2.1]octane-3-carboxylate::US20240351997, Example 125

SMILES O=C(OCCc1c[nH]c(=O)c(C(F)(F)F)c1)N1CC2CCC(C1)N2c1ncc(C(F)(F)F)cn1

InChI Key InChIKey=NFDDXAFVIFPWDX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 701395   

TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Shanghai Qilu Pharmaceutical Research And Development Centre

US Patent
LigandPNGBDBM701395(2-(6-Oxo-5-(trifluoromethyl)-1,6-dihydropyridin-3-...)
Affinity DataIC50: 0.710nMAssay Description:1. Preparation of 384-well histone-coated plate: 25 μL of histone solution was added to each well, and the plate was incubated overnight at 4° C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2025
Entry Details
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