BDBM701371 (S)-1-(6-Oxo-5-(trifluoromethyl)-1,6-dihydropyridin-3-yl)propan-2-yl 4-(5-(2-hydroxypropan-2-yl)pyrimidin-2-yl)piperazine-1-carboxylate::US20240351997, Example 100

SMILES C[C@@H](Cc1c[nH]c(=O)c(C(F)(F)F)c1)OC(=O)N1CCN(c2ncc(C(C)(C)O)cn2)CC1

InChI Key InChIKey=SUPPUJUPYLXULJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 701371   

TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Shanghai Qilu Pharmaceutical Research And Development Centre

US Patent
LigandPNGBDBM701371((S)-1-(6-Oxo-5-(trifluoromethyl)-1,6-dihydropyridi...)
Affinity DataIC50: 0.610nMAssay Description:1. Preparation of 384-well histone-coated plate: 25 μL of histone solution was added to each well, and the plate was incubated overnight at 4° C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2025
Entry Details
Go to US Patent