BDBM701336 5-(3-Methyl-5-(4-(5-(trifluoromethyl)pyrimidin-2-yl)piperazine-1-carbonyl)benzyl)-3-(trifluoromethyl)pyridin-2(1H)-one::US20240351997, Example 61

SMILES Cc1cc(Cc2c[nH]c(=O)c(C(F)(F)F)c2)cc(C(=O)N2CCN(c3ncc(C(F)(F)F)cn3)CC2)c1

InChI Key InChIKey=NVXRYTFBMWYOCH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 701336   

TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Shanghai Qilu Pharmaceutical Research And Development Centre

US Patent
LigandPNGBDBM701336(5-(3-Methyl-5-(4-(5-(trifluoromethyl)pyrimidin-2-y...)
Affinity DataIC50: 0.720nMAssay Description:1. Preparation of 384-well histone-coated plate: 25 μL of histone solution was added to each well, and the plate was incubated overnight at 4° C...More data for this Ligand-Target Pair
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Date in BDB:
3/2/2025
Entry Details
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