BDBM701280 US12123010, Compound Uracilpyridine 8

SMILES CCOC(=O)COc1ccccc1Oc1nc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1F

InChI Key InChIKey=KDHZPBIHBHHMLE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 701280   

TargetProtoporphyrinogen oxidase [F420M](Rough-fruited waterhemp)
Basf

US Patent
LigandPNGBDBM701280(US12123010, Compound Uracilpyridine 8)
Affinity DataIC50: 69.1nMAssay Description:Proto is purchased from Sigma-Aldrich (Milwaukee, WI). Protogen is prepared according to Jacobs and Jacobs (N. J. Jacobs, J. M. Jacobs, Assay for enz...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/25/2025
Entry Details
Go to US Patent

TargetProtoporphyrinogen oxidase [R128A,F420V](Rough-fruited waterhemp)
Basf

US Patent
LigandPNGBDBM701280(US12123010, Compound Uracilpyridine 8)
Affinity DataIC50: 2.25E+3nMAssay Description:Proto is purchased from Sigma-Aldrich (Milwaukee, WI). Protogen is prepared according to Jacobs and Jacobs (N. J. Jacobs, J. M. Jacobs, Assay for enz...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/25/2025
Entry Details
Go to US Patent

TargetProtoporphyrinogen oxidase(Rough-fruited waterhemp)
Basf

US Patent
LigandPNGBDBM701280(US12123010, Compound Uracilpyridine 8)
Affinity DataIC50: 0.496nMAssay Description:Proto is purchased from Sigma-Aldrich (Milwaukee, WI). Protogen is prepared according to Jacobs and Jacobs (N. J. Jacobs, J. M. Jacobs, Assay for enz...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/25/2025
Entry Details
Go to US Patent