BDBM701276 US12123010, Compound Uracilpyridine 1

SMILES CCOC(=O)COc1ncccc1Oc1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1Cl

InChI Key InChIKey=XPEVJXBWHXAUDR-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 701276   

TargetProtoporphyrinogen oxidase [F420M](Rough-fruited waterhemp)
Basf

US Patent
LigandPNGBDBM701276(US12123010, Compound Uracilpyridine 1)
Affinity DataIC50: 46.9nMAssay Description:Proto is purchased from Sigma-Aldrich (Milwaukee, WI). Protogen is prepared according to Jacobs and Jacobs (N. J. Jacobs, J. M. Jacobs, Assay for enz...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/25/2025
Entry Details
Go to US Patent

TargetProtoporphyrinogen oxidase [F420V](Rough-fruited waterhemp)
Basf

US Patent
LigandPNGBDBM701276(US12123010, Compound Uracilpyridine 1)
Affinity DataIC50: 66.4nMAssay Description:Proto is purchased from Sigma-Aldrich (Milwaukee, WI). Protogen is prepared according to Jacobs and Jacobs (N. J. Jacobs, J. M. Jacobs, Assay for enz...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/25/2025
Entry Details
Go to US Patent

TargetProtoporphyrinogen oxidase [L397Q](Rough-fruited waterhemp)
Basf

US Patent
LigandPNGBDBM701276(US12123010, Compound Uracilpyridine 1)
Affinity DataIC50: 2.38nMAssay Description:Proto is purchased from Sigma-Aldrich (Milwaukee, WI). Protogen is prepared according to Jacobs and Jacobs (N. J. Jacobs, J. M. Jacobs, Assay for enz...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/25/2025
Entry Details
Go to US Patent

TargetProtoporphyrinogen oxidase [L397Q,F420M](Rough-fruited waterhemp)
Basf

US Patent
LigandPNGBDBM701276(US12123010, Compound Uracilpyridine 1)
Affinity DataIC50: 429nMAssay Description:Proto is purchased from Sigma-Aldrich (Milwaukee, WI). Protogen is prepared according to Jacobs and Jacobs (N. J. Jacobs, J. M. Jacobs, Assay for enz...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/25/2025
Entry Details
Go to US Patent

TargetProtoporphyrinogen oxidase [L397Q,F420V](Rough-fruited waterhemp)
Basf

US Patent
LigandPNGBDBM701276(US12123010, Compound Uracilpyridine 1)
Affinity DataIC50: 2.26E+3nMAssay Description:Proto is purchased from Sigma-Aldrich (Milwaukee, WI). Protogen is prepared according to Jacobs and Jacobs (N. J. Jacobs, J. M. Jacobs, Assay for enz...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/25/2025
Entry Details
Go to US Patent

TargetProtoporphyrinogen oxidase [R128A,F420M](Rough-fruited waterhemp)
Basf

US Patent
LigandPNGBDBM701276(US12123010, Compound Uracilpyridine 1)
Affinity DataIC50: 61.6nMAssay Description:Proto is purchased from Sigma-Aldrich (Milwaukee, WI). Protogen is prepared according to Jacobs and Jacobs (N. J. Jacobs, J. M. Jacobs, Assay for enz...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/25/2025
Entry Details
Go to US Patent

TargetProtoporphyrinogen oxidase [R128A,F420V](Rough-fruited waterhemp)
Basf

US Patent
LigandPNGBDBM701276(US12123010, Compound Uracilpyridine 1)
Affinity DataIC50: 162nMAssay Description:Proto is purchased from Sigma-Aldrich (Milwaukee, WI). Protogen is prepared according to Jacobs and Jacobs (N. J. Jacobs, J. M. Jacobs, Assay for enz...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/25/2025
Entry Details
Go to US Patent

TargetProtoporphyrinogen oxidase(Rough-fruited waterhemp)
Basf

US Patent
LigandPNGBDBM701276(US12123010, Compound Uracilpyridine 1)
Affinity DataIC50: 0.177nMAssay Description:Proto is purchased from Sigma-Aldrich (Milwaukee, WI). Protogen is prepared according to Jacobs and Jacobs (N. J. Jacobs, J. M. Jacobs, Assay for enz...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/25/2025
Entry Details
Go to US Patent