BDBM701272 US12122780, Compound 41

SMILES COC1(COc2cnc(-c3cccc(Cn4c(=O)ccn5c6cc(C#N)ccc6nc45)c3)nc2)CCN(CCO)CC1

InChI Key InChIKey=BGBZZWKMIFCVIU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 701272   

TargetHepatocyte growth factor receptor(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandPNGBDBM701272(US12122780, Compound 41)
Affinity DataIC50: 6.63nMAssay Description:The kinase buffer in the kit was used to dilute the enzyme, substrate, ATP and inhibitor.The compound to be tested was diluted 5-fold to the eighth c...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/24/2025
Entry Details
Go to US Patent