BDBM701262 US12122780, Compound 27

SMILES CN1CCC(COc2cnc(-c3cccc(Cn4c(=O)ccc5c4nn4ccc(C#N)cc54)c3)nc2)CC1

InChI Key InChIKey=SJONSQPWWBNENP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 701262   

TargetHepatocyte growth factor receptor(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandPNGBDBM701262(US12122780, Compound 27)
Affinity DataIC50: 17.7nMAssay Description:The kinase buffer in the kit was used to dilute the enzyme, substrate, ATP and inhibitor.The compound to be tested was diluted 5-fold to the eighth c...More data for this Ligand-Target Pair
Ligand InfoSimilars
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Date in BDB:
2/24/2025
Entry Details
Go to US Patent