BDBM701233 4-[2-(N-(3,3-difluorocyclohexyl)anilino)-2- oxo-ethyl]-1-[1-(2- fluorophenyl)cyclopropanecarbonyl]piperidine- 4-carboxylic acid::US12122750, Example 66

SMILES O=C(CC1(C(=O)O)CCN(C(=O)C2(c3ccccc3F)CC2)CC1)N(c1ccccc1)C1CCCC(F)(F)C1

InChI Key InChIKey=UVZPAXDMYYTAJJ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 701233   

TargetType-2 angiotensin II receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM701233(4-[2-(N-(3,3-difluorocyclohexyl)anilino)-2- oxo-et...)
Affinity DataKi:  0.619nMAssay Description:Receptor binding affinities (Ki) were determined from a competitive radioligand binding assay with human recombinant ([125I]-Tyr4)-Angiotensin-II (22...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/24/2025
Entry Details
Go to US Patent

TargetType-1 angiotensin II receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM701233(4-[2-(N-(3,3-difluorocyclohexyl)anilino)-2- oxo-et...)
Affinity DataKi:  3.73E+4nMAssay Description:Receptor binding affinities (Ki) were determined from a competitive radioligand binding assay with human recombinant ([125I]-Tyr4)-Angiotensin-II (22...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/24/2025
Entry Details
Go to US Patent