BDBM701154 US12122780, Compound 1

SMILES CN1CCC(COc2cnc(-c3cccc(Cn4c5c(ccc4=O)-c4cc(C#N)ccc4C5(F)F)c3)nc2)CC1

InChI Key InChIKey=VOMHVFJITXGLAE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 701154   

TargetHepatocyte growth factor receptor(Human)
Jiangsu Aosaikang Pharmaceutical

US Patent
LigandPNGBDBM701154(US12122780, Compound 1)
Affinity DataIC50: 42nMAssay Description:The kinase buffer in the kit was used to dilute the enzyme, substrate, ATP and inhibitor.The compound to be tested was diluted 5-fold to the eighth c...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/24/2025
Entry Details
Go to US Patent