BDBM701144 US12122742, Compound I-a-8

SMILES COc1ccc(S(=O)(=O)C(C(=O)O)c2cc(Sc3ccccc3)c(N(C(=O)O)S(=O)(=O)c3ccc(OC)cc3)c3ccccc23)cc1

InChI Key InChIKey=HAHIZMFAOMSGQP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 701144   

TargetKelch-like ECH-associated protein 1/Nuclear factor erythroid 2-related factor 2(Human)
Rutgers, The State University of New Jersey

US Patent
LigandPNGBDBM701144(US12122742, Compound I-a-8)
Affinity DataIC50: 90nMAssay Description:Fluorescence polarization assay was performed on a Wallac Victor 3V multi-label counter/plate reader (PerkinElmer, Shelton, CT) using 484 nm excitati...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/24/2025
Entry Details
Go to US Patent

TargetKelch-like ECH-associated protein 1/Nuclear factor erythroid 2-related factor 2(Human)
Rutgers, The State University of New Jersey

US Patent
LigandPNGBDBM701144(US12122742, Compound I-a-8)
Affinity DataIC50: 7.10nMAssay Description:TR-FRET assay was performed on a Wallac Victor 3V multi-label counter/plate reader (PerkinElmer, Shelton, CT). The plate used for the FP measurement ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/24/2025
Entry Details
Go to US Patent