BDBM701142 US12122742, Compound I-a-6

SMILES COc1ccc(-c2cc(C(C(=O)O)S(=O)(=O)c3ccc(OC)cc3)c3ccccc3c2N(C(=O)O)S(=O)(=O)c2ccc(OC)cc2)cc1

InChI Key InChIKey=CVRATQOGVGVSRY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 701142   

TargetKelch-like ECH-associated protein 1/Nuclear factor erythroid 2-related factor 2(Human)
Rutgers, The State University of New Jersey

US Patent
LigandPNGBDBM701142(US12122742, Compound I-a-6)
Affinity DataIC50: 85nMAssay Description:Fluorescence polarization assay was performed on a Wallac Victor 3V multi-label counter/plate reader (PerkinElmer, Shelton, CT) using 484 nm excitati...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/24/2025
Entry Details
Go to US Patent

TargetKelch-like ECH-associated protein 1/Nuclear factor erythroid 2-related factor 2(Human)
Rutgers, The State University of New Jersey

US Patent
LigandPNGBDBM701142(US12122742, Compound I-a-6)
Affinity DataIC50: 13.1nMAssay Description:TR-FRET assay was performed on a Wallac Victor 3V multi-label counter/plate reader (PerkinElmer, Shelton, CT). The plate used for the FP measurement ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/24/2025
Entry Details
Go to US Patent