BDBM701091 US20240343729, Example 6

SMILES Cn1cc(-c2ccccc2)nc1C#Cc1nc(N2CC3(COC3)C2)c2cnn(C3CCOCC3)c2n1

InChI Key InChIKey=NTDMDXJVLTYFBM-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 701091   

TargetIsoform PDE10A2 of cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (PDE10A2)(Human)
Benevolentai Cambridge

US Patent

LigandBDBM701091(US20240343729, Example 6)Copy SMILESCopy InChI

Affinity DataIC50: 0.631nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
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Ligand InfoSimilars

In Depth
Date in BDB:
2/23/2025
Entry Details
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