BDBM700954 N-(2,3-dimethyl-6-nitrophenyl)- N-methylacetamide::US20240343694, Example 84

SMILES CC(=O)N(C)c1c([N+](=O)[O-])ccc(C)c1C

InChI Key InChIKey=YYFXDJZLXVIKOY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 700954   

TargetEpidermal growth factor receptor [1-18,20-1210](Human)
Korea Reserarch Institute of Chemical Technology

US Patent
LigandPNGBDBM700954(N-(2,3-dimethyl-6-nitrophenyl)- N-methylacetamide ...)
Affinity DataIC50: 1nMAssay Description:The activity of the compounds of the present invention against EGFR mutant enzymes was measured using the HTRF system purchased from Cisbio as follow...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [1-763,'FHEA',764-1210](Human)
Korea Reserarch Institute of Chemical Technology

US Patent
LigandPNGBDBM700954(N-(2,3-dimethyl-6-nitrophenyl)- N-methylacetamide ...)
Affinity DataIC50: 3nMAssay Description:The activity of the compounds of the present invention against EGFR mutant enzymes was measured using the HTRF system purchased from Cisbio as follow...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-2 [1-775,'YVMA',776-1255](Human)
Korea Reserarch Institute of Chemical Technology

US Patent
LigandPNGBDBM700954(N-(2,3-dimethyl-6-nitrophenyl)- N-methylacetamide ...)
Affinity DataIC50: 52nMAssay Description:The activity of the compounds of the present invention against HER mutant enzymes was measured using the HTRF system purchased by Cisbio as follows. ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/23/2025
Entry Details
US Patent