BDBM700543 US20240336629, Compound 68B

SMILES COC[C@@H](COCCC(=O)N1CCN2[C@H](C1)CCOc1cc(cnc21)C(F)(F)F)Nc1cn[nH]c(=O)c1C(F)(F)F

InChI Key InChIKey=XZJYBMADQLZNRL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 700543   

TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM700543(US20240336629, Compound 68B)
Affinity DataIC50: 4.29nMAssay Description:(1) Each compound to be tested was prepared using gradient dilution method with DMSO and water to obtain a solution with the concentration of 50 nM, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProtein mono-ADP-ribosyltransferase TIPARP(Human)
Jacobio Pharmaceuticals

US Patent
LigandPNGBDBM700543(US20240336629, Compound 68B)
Affinity DataIC50: 1.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Hubei Polytechnic University

Curated by ChEMBL
LigandPNGBDBM700543(US20240336629, Compound 68B)
Affinity DataIC50: 2.32E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed