BDBM700361 1-(4-((6-(trans-4-(3,4-dihydroisoquinolin-2(1H)-yl)-3-hydroxypiperidine-1-carbonyl)-2-methoxypyrimidin-4-yl)amino)piperidin-1-yl)ethan-1-one::US20240336593, Example 120::US20250206717, Example 268

SMILES COc1nc(NC2CCN(CC2)C(C)=O)cc(n1)C(=O)N1CC[C@@H]([C@@H](O)C1)N1CCc2ccccc2C1

InChI Key InChIKey=QELAPYWIXWBYDH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 700361   

TargetProtein arginine N-methyltransferase 5(Human)
Lnnovstonetherapeutics

US Patent
LigandPNGBDBM700361(US20240336593, Example 120 | 1-(4-((6-(trans-4-(3,...)
Affinity DataIC50: 100nMAssay Description:Test method: A 1× enzyme reaction buffer (10 mM Tris 8.0 (Sigma, Cat. No. T2694-1L), 0.01% Tween-20 (Sigma, Cat. No. P2287-100 ML), 1 mM DTT (Sigma, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
Go to US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Lnnovstonetherapeutics

US Patent
LigandPNGBDBM700361(US20240336593, Example 120 | 1-(4-((6-(trans-4-(3,...)
Affinity DataIC50: 75nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2025
Entry Details
Go to US Patent